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Active PKG II inhibited the growth and migration of ovarian cancer cells through blocking Raf/MEK and PI3K/Akt signaling pathways

Despite advances in chemotherapy, ovarian cancer (OC) is still the most lethal gynecologic malignancy. So, it is imperative to explore its mechanism and find novel targets to improve the outcome. Type II cyclic guanosine 3′,5′-monophosphate (cGMP)-dependent protein kinase (PKG II) has been recently...

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Detalles Bibliográficos
Autores principales:	Wu, Yan, Cai, Qin, Li, Wei, Cai, Zhensheng, Liu, Ying, Li, Hongfan, Pang, Ji, Chen, Yongchang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692568/ https://www.ncbi.nlm.nih.gov/pubmed/31350342 http://dx.doi.org/10.1042/BSR20190405

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