Overexpression of SMYD3 in Ovarian Cancer is Associated with Ovarian Cancer Proliferation and Apoptosis via Methylating H3K4 and H4K20

Background: Epigenetic regulation has been verified as a key mechanism in tumorigenesis. SET and MYND domain-containing protein 3 (SMYD3), a histone methyltransferase, is a promising epigenetic therapeutic target and is overexpressed in numerous human tumors. SMYD3 can promote oncogenic progression...

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Detalles Bibliográficos
Autores principales: Jiang, Yahui, Lyu, Tianjiao, Che, Xiaoxia, Jia, Nan, Li, Qin, Feng, Weiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692630/
https://www.ncbi.nlm.nih.gov/pubmed/31417652
http://dx.doi.org/10.7150/jca.29861

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