Cargando…

A Genetic Locus on Chromosome 2q24 Predicting Peripheral Neuropathy Risk in Type 2 Diabetes: Results From the ACCORD and BARI 2D Studies

Genetic factors have been postulated to be involved in the etiology of diabetic peripheral neuropathy (DPN), but their identity remains mostly unknown. The aim of this study was to conduct a systematic search for genetic variants influencing DPN risk using two well-characterized cohorts. A genome-wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Yaling, Lenzini, Petra A., Pop-Busui, Rodica, Ray, Pradipta R., Campbell, Hannah, Perkins, Bruce A., Callaghan, Brian, Wagner, Michael J., Motsinger-Reif, Alison A., Buse, John B., Price, Theodore J., Mychaleckyj, Josyf C., Cresci, Sharon, Shah, Hetal, Doria, Alessandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2019
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692816/ https://www.ncbi.nlm.nih.gov/pubmed/31127053 http://dx.doi.org/10.2337/db19-0109

Ejemplares similares

Gene Expression Differences in Skin Fibroblasts in Identical Twins Discordant for Type 1 Diabetes
por: Caramori, M. Luiza, et al.
Publicado: (2012)

Impact of Glycemic Control Strategies on the Progression of Diabetic Peripheral Neuropathy in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Cohort
por: Pop-Busui, Rodica, et al.
Publicado: (2013)

Synergism Between Circulating Tumor Necrosis Factor Receptor 2 and HbA(1c) in Determining Renal Decline During 5–18 Years of Follow-up in Patients With Type 1 Diabetes and Proteinuria
por: Skupien, Jan, et al.
Publicado: (2014)

Prevalence of and Risk Factors for Diabetic Peripheral Neuropathy in Youth With Type 1 and Type 2 Diabetes: SEARCH for Diabetes in Youth Study
por: Jaiswal, Mamta, et al.
Publicado: (2017)

Association Between Impaired Cardiovascular Autonomic Function and Hypoglycemia in Patients With Type 1 Diabetes
por: Jaiswal, Mamta, et al.
Publicado: (2014)

‘You have to use everything and come to some equilibrium’: a qualitative study on hypoglycemia self-management in users of continuous glucose monitor with diverse hypoglycemia experiences
por: Lin, Yu Kuei, et al.
Publicado: (2023)

Association of Glycemic Variability in Type 1 Diabetes With Progression of Microvascular Outcomes in the Diabetes Control and Complications Trial
por: Lachin, John M., et al.
Publicado: (2017)

Modulation of GLP-1 Levels by a Genetic Variant That Regulates the Cardiovascular Effects of Intensive Glycemic Control in ACCORD
por: Shah, Hetal S., et al.
Publicado: (2018)

Progressive Axonal Dysfunction Precedes Development of Neuropathy in Type 2 Diabetes
por: Sung, Jia-Ying, et al.
Publicado: (2012)

PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid
por: Morieri, Mario Luca, et al.
Publicado: (2020)

Transcriptional Profiling of Diabetic Neuropathy in the BKS db/db Mouse: A Model of Type 2 Diabetes
por: Pande, Manjusha, et al.
Publicado: (2011)

Higher frequency of cardiovascular autonomic neuropathy in youth with type 2 compared to type 1 diabetes: Role of cardiometabolic risk factors
por: Varley, Benjamin J., et al.
Publicado: (2022)

Increased Intraretinal PO(2) in Short-Term Diabetic Rats
por: Lau, Jennifer C.M., et al.
Publicado: (2014)

Correction of HDL Dysfunction in Individuals With Diabetes and the Haptoglobin 2-2 Genotype
por: Asleh, Rabea, et al.
Publicado: (2008)

Sex Differences in Coronary Microvascular Function in Individuals With Type 2 Diabetes
por: Haas, Andrea V., et al.
Publicado: (2019)

Arginase-2 Mediates Diabetic Renal Injury
por: Morris, Sidney M., et al.
Publicado: (2011)

c-Jun NH(2)-Terminal Kinase 1/2 and Endoplasmic Reticulum Stress as Interdependent and Reciprocal Causation in Diabetic Embryopathy
por: Li, Xuezheng, et al.
Publicado: (2013)

Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial
por: Morieri, Mario Luca, et al.
Publicado: (2018)

Activation of NF-E2–Related Factor-2 Reverses Biochemical Dysfunction of Endothelial Cells Induced by Hyperglycemia Linked to Vascular Disease
por: Xue, Mingzhan, et al.
Publicado: (2008)

Genetic Predictors of Cardiovascular Mortality During Intensive Glycemic Control in Type 2 Diabetes: Findings From the ACCORD Clinical Trial
por: Shah, Hetal S., et al.
Publicado: (2016)

Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo
por: Bharath, Leena P., et al.
Publicado: (2015)

Task-Induced Brain Activity Patterns in Type 2 Diabetes: A Potential Biomarker for Cognitive Decline
por: Marder, Thomas J., et al.
Publicado: (2014)

Macrophage Cyclooxygenase-2 Protects Against Development of Diabetic Nephropathy
por: Wang, Xin, et al.
Publicado: (2017)

Decreased IRS2 and TIMP3 Expression in Monocytes From Offspring of Type 2 Diabetic Patients Is Correlated With Insulin Resistance and Increased Intima-Media Thickness
por: Cardellini, Marina, et al.
Publicado: (2011)

Catalase Overexpression Prevents Nuclear Factor Erythroid 2–Related Factor 2 Stimulation of Renal Angiotensinogen Gene Expression, Hypertension, and Kidney Injury in Diabetic Mice
por: Abdo, Shaaban, et al.
Publicado: (2014)

Early-Outgrowth Bone Marrow Cells Attenuate Renal Injury and Dysfunction via an Antioxidant Effect in a Mouse Model of Type 2 Diabetes
por: Zhang, Yanling, et al.
Publicado: (2012)

Spinal Disinhibition in Experimental and Clinical Painful Diabetic Neuropathy
por: Marshall, Andrew G., et al.
Publicado: (2017)

Resting-State Brain Functional Connectivity Is Altered in Type 2 Diabetes
por: Musen, Gail, et al.
Publicado: (2012)

Cardiac Autonomic Neuropathy in Diabetes: A clinical perspective
por: Pop-Busui, Rodica
Publicado: (2010)

Epigenetic Changes in Bone Marrow Progenitor Cells Influence the Inflammatory Phenotype and Alter Wound Healing in Type 2 Diabetes
por: Gallagher, Katherine A., et al.
Publicado: (2015)

Ceramide Mediates Vascular Dysfunction in Diet-Induced Obesity by PP2A-Mediated Dephosphorylation of the eNOS-Akt Complex
por: Zhang, Quan-Jiang, et al.
Publicado: (2012)

Inhibition of TNF-α Improves the Bladder Dysfunction That Is Associated With Type 2 Diabetes
por: Wang, Zongwei, et al.
Publicado: (2012)

Per2 Mutation Recapitulates the Vascular Phenotype of Diabetes in the Retina and Bone Marrow
por: Bhatwadekar, Ashay D., et al.
Publicado: (2013)

The Metabolic Syndrome and Microvascular Complications in a Murine Model of Type 2 Diabetes
por: Hur, Junguk, et al.
Publicado: (2015)

Metallothionein Is Downstream of Nrf2 and Partially Mediates Sulforaphane Prevention of Diabetic Cardiomyopathy
por: Gu, Junlian, et al.
Publicado: (2017)

The Role of Prostaglandins in Disrupted Gastric Motor Activity Associated With Type 2 Diabetes
por: Blair, Peter J., et al.
Publicado: (2019)

Targeted Reduction of Vascular Msx1 and Msx2 Mitigates Arteriosclerotic Calcification and Aortic Stiffness in LDLR-Deficient Mice Fed Diabetogenic Diets
por: Cheng, Su-Li, et al.
Publicado: (2014)

Protective Role of Cannabinoid Receptor Type 2 in a Mouse Model of Diabetic Nephropathy
por: Barutta, Federica, et al.
Publicado: (2011)

Mineralocorticoid Receptor Blockade Improves Coronary Microvascular Function in Individuals With Type 2 Diabetes
por: Garg, Rajesh, et al.
Publicado: (2015)

Insulin Downregulates the Transcriptional Coregulator CITED2, an Inhibitor of Proangiogenic Function in Endothelial Cells
por: Wang, Xuanchun, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1kfp4dppd31k9atef0lb9vt61h