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Topical Administration of a Soluble TNF Inhibitor Reduces Infarct Volume After Focal Cerebral Ischemia in Mice

BACKGROUND: Tumor necrosis factor, which exists both as a soluble (solTNF) and a transmembrane (tmTNF) protein, plays an important role in post-stroke inflammation. The objective of the present study was to test the effect of topical versus intracerebroventricular administration of XPro1595 (a solTN...

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Detalles Bibliográficos
Autores principales:	Yli-Karjanmaa, Minna, Clausen, Bettina Hjelm, Degn, Matilda, Novrup, Hans Gram, Ellman, Ditte Gry, Toft-Jensen, Peter, Szymkowski, David E., Stensballe, Allan, Meyer, Morten, Brambilla, Roberta, Lambertsen, Kate Lykke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692878/ https://www.ncbi.nlm.nih.gov/pubmed/31440125 http://dx.doi.org/10.3389/fnins.2019.00781

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