Cargando…
Inhibition of CD133 Overcomes Cisplatin Resistance Through Inhibiting PI3K/AKT/mTOR Signaling Pathway and Autophagy in CD133-Positive Gastric Cancer Cells
Cisplatin is widely used as the standard gastric cancer treatment, but the relapse and metastasis are common as intrinsic or acquired drug resistance. CD133 has been widely known to be associated with chemoresistance in various cancer cells. In this study, we focused on investigating the function an...
Autores principales: | Lu, Ruiqi, Zhao, Gang, Yang, Yulong, Jiang, Zhaoyan, Cai, Jingli, Hu, Hai |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693020/ https://www.ncbi.nlm.nih.gov/pubmed/31405336 http://dx.doi.org/10.1177/1533033819864311 |
Ejemplares similares
-
Transient mTOR Inhibition Facilitates Continuous Growth of Liver Tumors by Modulating the Maintenance of CD133+ Cell Populations
por: Yang, Zhaojuan, et al.
Publicado: (2011) -
Oxytetracycline have the therapeutic efficiency in CD133(+) HCC population through suppression CD133 expression by decreasing of protein stability of CD133
por: Song, Yeonhwa, et al.
Publicado: (2018) -
miR-200b inhibits CD133(+) glioma cells by targeting the AKT pathway
por: Liu, Aiqun, et al.
Publicado: (2017) -
Osthole resensitizes CD133(+) hepatocellular carcinoma cells to cisplatin treatment via PTEN/AKT pathway
por: Ye, Junfeng, et al.
Publicado: (2020) -
Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells
por: Friel, Anne M, et al.
Publicado: (2010)