Homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention

We successfully treated a patient with homozygous familial hypercholesterolemia (HoFH) with stable coronary arterial disease using optimal medical therapy and low‐density lipoprotein (LDL) apheresis for 16 years without percutaneous coronary intervention or bypass surgery. Intensive LDL lowering usi...

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Autores principales: Yasu, Takanori, Shimoyama, Masahiro, Wada, Hiroshi, Iwakura, Tomohiro, Toyoda, Shigeru, Kawabe, Atsuhiko, Sugiyama, Takushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693054/
https://www.ncbi.nlm.nih.gov/pubmed/31428402
http://dx.doi.org/10.1002/ccr3.2299
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author Yasu, Takanori
Shimoyama, Masahiro
Wada, Hiroshi
Iwakura, Tomohiro
Toyoda, Shigeru
Kawabe, Atsuhiko
Sugiyama, Takushi
author_facet Yasu, Takanori
Shimoyama, Masahiro
Wada, Hiroshi
Iwakura, Tomohiro
Toyoda, Shigeru
Kawabe, Atsuhiko
Sugiyama, Takushi
author_sort Yasu, Takanori
collection PubMed
description We successfully treated a patient with homozygous familial hypercholesterolemia (HoFH) with stable coronary arterial disease using optimal medical therapy and low‐density lipoprotein (LDL) apheresis for 16 years without percutaneous coronary intervention or bypass surgery. Intensive LDL lowering using apheresis and medication protected the patient from coronary atherosclerotic progression even in HoFH.
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spelling pubmed-66930542019-08-19 Homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention Yasu, Takanori Shimoyama, Masahiro Wada, Hiroshi Iwakura, Tomohiro Toyoda, Shigeru Kawabe, Atsuhiko Sugiyama, Takushi Clin Case Rep Case Reports We successfully treated a patient with homozygous familial hypercholesterolemia (HoFH) with stable coronary arterial disease using optimal medical therapy and low‐density lipoprotein (LDL) apheresis for 16 years without percutaneous coronary intervention or bypass surgery. Intensive LDL lowering using apheresis and medication protected the patient from coronary atherosclerotic progression even in HoFH. John Wiley and Sons Inc. 2019-07-16 /pmc/articles/PMC6693054/ /pubmed/31428402 http://dx.doi.org/10.1002/ccr3.2299 Text en © 2019 Dokkyo Medical University Nikko Medical Center. Clinical Case Reports Published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Reports
Yasu, Takanori
Shimoyama, Masahiro
Wada, Hiroshi
Iwakura, Tomohiro
Toyoda, Shigeru
Kawabe, Atsuhiko
Sugiyama, Takushi
Homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention
title Homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention
title_full Homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention
title_fullStr Homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention
title_full_unstemmed Homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention
title_short Homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention
title_sort homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693054/
https://www.ncbi.nlm.nih.gov/pubmed/31428402
http://dx.doi.org/10.1002/ccr3.2299
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