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360-Degree Complex Primary Reconstruction Using Porous Tantalum Cages for Adult Degenerative Spinal Deformity

STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To assess both implant performance and the amount of correction that can be achieved using multilevel anterior lumbar interbody fusion (ALIF). METHODS: Retrospective cohort study (n = 178) performed over a 4-year period. Surgical variables examine...

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Autores principales: Butler, Joseph S., Lui, Darren F., Malhotra, Karan, Suarez-Huerta, Maria L., Yu, Haiming, Selvadurai, Susanne, Agu, Obiekezie, Molloy, Sean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693065/
https://www.ncbi.nlm.nih.gov/pubmed/31448194
http://dx.doi.org/10.1177/2192568218814531
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author Butler, Joseph S.
Lui, Darren F.
Malhotra, Karan
Suarez-Huerta, Maria L.
Yu, Haiming
Selvadurai, Susanne
Agu, Obiekezie
Molloy, Sean
author_facet Butler, Joseph S.
Lui, Darren F.
Malhotra, Karan
Suarez-Huerta, Maria L.
Yu, Haiming
Selvadurai, Susanne
Agu, Obiekezie
Molloy, Sean
author_sort Butler, Joseph S.
collection PubMed
description STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To assess both implant performance and the amount of correction that can be achieved using multilevel anterior lumbar interbody fusion (ALIF). METHODS: Retrospective cohort study (n = 178) performed over a 4-year period. Surgical variables examined included blood loss, operative time, perioperative complications, and secondary/revision procedures. Follow-up radiographic assessment was performed to record implant-related problems. Radiographic parameters were examined pre- and postoperatively. Health-related quality of life (HRQOL) outcome measures were collected preoperatively and at 6 weeks, 6 months, 1 year, and 2 years postoperatively. Descriptive and comparative statistical analysis, using paired-sample t test and repeated-measures analysis of variance (rANOVA), was performed. RESULTS: Lumbar lordosis increased from 42° ± 17° preoperatively to 55° ± 11° postoperatively (P < .001). The visual analog scale back pain mean score improved from 8.3 ± 1.5 preoperatively to 2.6 ± 2.4 at 2 years (P < .001). The mean Oswestry Disability Index improved from 69.5 ± 21.5 preoperatively to 19.9 ± 15.2 at 2 years (P < .001). The EQ-5D mean score improved from 0.2 ± 0.2 preoperatively to 0.8 ± 0.1 at 2 years (P = .02). There were no neurological, vascular, or visceral approach–related injuries reported. No rod breakages and no symptomatic nonunions occurred. There was one revision procedure performed for fracture. CONCLUSIONS: The use of porous tantalum cages as part of a 360-degree fusion to treat adult degenerative spinal deformity has been demonstrated to be a safe and effective strategy, leading to good clinical, functional, and radiographic outcomes in the short term.
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spelling pubmed-66930652019-08-23 360-Degree Complex Primary Reconstruction Using Porous Tantalum Cages for Adult Degenerative Spinal Deformity Butler, Joseph S. Lui, Darren F. Malhotra, Karan Suarez-Huerta, Maria L. Yu, Haiming Selvadurai, Susanne Agu, Obiekezie Molloy, Sean Global Spine J Original Articles STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To assess both implant performance and the amount of correction that can be achieved using multilevel anterior lumbar interbody fusion (ALIF). METHODS: Retrospective cohort study (n = 178) performed over a 4-year period. Surgical variables examined included blood loss, operative time, perioperative complications, and secondary/revision procedures. Follow-up radiographic assessment was performed to record implant-related problems. Radiographic parameters were examined pre- and postoperatively. Health-related quality of life (HRQOL) outcome measures were collected preoperatively and at 6 weeks, 6 months, 1 year, and 2 years postoperatively. Descriptive and comparative statistical analysis, using paired-sample t test and repeated-measures analysis of variance (rANOVA), was performed. RESULTS: Lumbar lordosis increased from 42° ± 17° preoperatively to 55° ± 11° postoperatively (P < .001). The visual analog scale back pain mean score improved from 8.3 ± 1.5 preoperatively to 2.6 ± 2.4 at 2 years (P < .001). The mean Oswestry Disability Index improved from 69.5 ± 21.5 preoperatively to 19.9 ± 15.2 at 2 years (P < .001). The EQ-5D mean score improved from 0.2 ± 0.2 preoperatively to 0.8 ± 0.1 at 2 years (P = .02). There were no neurological, vascular, or visceral approach–related injuries reported. No rod breakages and no symptomatic nonunions occurred. There was one revision procedure performed for fracture. CONCLUSIONS: The use of porous tantalum cages as part of a 360-degree fusion to treat adult degenerative spinal deformity has been demonstrated to be a safe and effective strategy, leading to good clinical, functional, and radiographic outcomes in the short term. SAGE Publications 2018-11-21 2019-09 /pmc/articles/PMC6693065/ /pubmed/31448194 http://dx.doi.org/10.1177/2192568218814531 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc-nd/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 License (http://www.creativecommons.org/licenses/by-nc-nd/4.0/) which permits non-commercial use, reproduction and distribution of the work as published without adaptation or alteration, without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Articles
Butler, Joseph S.
Lui, Darren F.
Malhotra, Karan
Suarez-Huerta, Maria L.
Yu, Haiming
Selvadurai, Susanne
Agu, Obiekezie
Molloy, Sean
360-Degree Complex Primary Reconstruction Using Porous Tantalum Cages for Adult Degenerative Spinal Deformity
title 360-Degree Complex Primary Reconstruction Using Porous Tantalum Cages for Adult Degenerative Spinal Deformity
title_full 360-Degree Complex Primary Reconstruction Using Porous Tantalum Cages for Adult Degenerative Spinal Deformity
title_fullStr 360-Degree Complex Primary Reconstruction Using Porous Tantalum Cages for Adult Degenerative Spinal Deformity
title_full_unstemmed 360-Degree Complex Primary Reconstruction Using Porous Tantalum Cages for Adult Degenerative Spinal Deformity
title_short 360-Degree Complex Primary Reconstruction Using Porous Tantalum Cages for Adult Degenerative Spinal Deformity
title_sort 360-degree complex primary reconstruction using porous tantalum cages for adult degenerative spinal deformity
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693065/
https://www.ncbi.nlm.nih.gov/pubmed/31448194
http://dx.doi.org/10.1177/2192568218814531
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