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A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with myocardial infarction in type 2 diabetic patients

BACKGROUND: Myocardial infarction is the main mortality cause in patients with type 2 diabetes (T2DM). Endothelial dysfunction due to reduced bioavailability of nitric oxide (NO) is an early step of atherogenesis. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of NO synthesis, and it...

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Detalles Bibliográficos
Autores principales:	Mannino, Gaia Chiara, Pezzilli, Serena, Averta, Carolina, Fuoco, Anastasia, Spiga, Rosangela, Mancuso, Elettra, Di Fatta, Concetta, Perticone, Francesco, Prudente, Sabrina, Trischitta, Vincenzo, Andreozzi, Francesco, Sesti, Giorgio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693196/ https://www.ncbi.nlm.nih.gov/pubmed/31409409 http://dx.doi.org/10.1186/s12933-019-0906-1

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