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IL-21 Induces an Imbalance of Th17/Treg Cells in Moderate-to-Severe Plaque Psoriasis Patients

Background: Psoriasis is a chronic immune-mediated inflammatory skin disease, with over-activated interleukin (IL)-17-producing CD4(+) T cells (Th17) and repressed regulatory T (Treg) cells. IL-21 is a Th17-related cytokine and plays an important role in the pathogenesis of psoriasis. However, the m...

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Detalles Bibliográficos
Autores principales:	Shi, Yuling, Chen, Zeyu, Zhao, Zihan, Yu, Yingyuan, Fan, Huayu, Xu, Xiaoguang, Bu, Xiaolin, Gu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693306/ https://www.ncbi.nlm.nih.gov/pubmed/31440249 http://dx.doi.org/10.3389/fimmu.2019.01865

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