Modifications of the Transcriptomic Profile of Autoreactive B Cells From Pemphigus Patients After Treatment With Rituximab or a Standard Corticosteroid Regimen

Pemphigus Vulgaris is an autoimmune disease of the skin and mucous membranes, which is due to the production of pathogenic autoantibodies targeting desmoglein (DSG) 1 and 3, which are adhesion proteins of the keratinocytes. Rituximab is an anti-CD20 mAb which induces a prolonged depletion of blood B...

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Detalles Bibliográficos
Autores principales: Hébert, Vivien, Petit, Marie, Maho-Vaillant, Maud, Golinski, Marie-Laure, Riou, Gaëtan, Derambure, Céline, Boyer, Olivier, Joly, Pascal, Calbo, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693356/
https://www.ncbi.nlm.nih.gov/pubmed/31440235
http://dx.doi.org/10.3389/fimmu.2019.01794

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