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Installation of -SO(2)F groups onto primary amides
A protocol of SO(2)F(2)-mediated installation of sulfonyl fluoride onto primary amides has been developed providing a new portal to sulfur(VI) fluoride exchange (SuFEx) click chemistry. The generated molecules contain pharmaceutically important amide and -SO(2)F moieties for application in the disco...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693406/ https://www.ncbi.nlm.nih.gov/pubmed/31467612 http://dx.doi.org/10.3762/bjoc.15.186 |
| _version_ | 1783443702298968064 |
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| author | Liu, Jing Wang, Shi-Meng Alharbi, Njud S Qin, Hua-Li |
| author_facet | Liu, Jing Wang, Shi-Meng Alharbi, Njud S Qin, Hua-Li |
| author_sort | Liu, Jing |
| collection | PubMed |
| description | A protocol of SO(2)F(2)-mediated installation of sulfonyl fluoride onto primary amides has been developed providing a new portal to sulfur(VI) fluoride exchange (SuFEx) click chemistry. The generated molecules contain pharmaceutically important amide and -SO(2)F moieties for application in the discovery of new therapeutics. |
| format | Online Article Text |
| id | pubmed-6693406 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2019 |
| publisher | Beilstein-Institut |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-66934062019-08-29 Installation of -SO(2)F groups onto primary amides Liu, Jing Wang, Shi-Meng Alharbi, Njud S Qin, Hua-Li Beilstein J Org Chem Letter A protocol of SO(2)F(2)-mediated installation of sulfonyl fluoride onto primary amides has been developed providing a new portal to sulfur(VI) fluoride exchange (SuFEx) click chemistry. The generated molecules contain pharmaceutically important amide and -SO(2)F moieties for application in the discovery of new therapeutics. Beilstein-Institut 2019-08-09 /pmc/articles/PMC6693406/ /pubmed/31467612 http://dx.doi.org/10.3762/bjoc.15.186 Text en Copyright © 2019, Liu et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
| spellingShingle | Letter Liu, Jing Wang, Shi-Meng Alharbi, Njud S Qin, Hua-Li Installation of -SO(2)F groups onto primary amides |
| title | Installation of -SO(2)F groups onto primary amides |
| title_full | Installation of -SO(2)F groups onto primary amides |
| title_fullStr | Installation of -SO(2)F groups onto primary amides |
| title_full_unstemmed | Installation of -SO(2)F groups onto primary amides |
| title_short | Installation of -SO(2)F groups onto primary amides |
| title_sort | installation of -so(2)f groups onto primary amides |
| topic | Letter |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693406/ https://www.ncbi.nlm.nih.gov/pubmed/31467612 http://dx.doi.org/10.3762/bjoc.15.186 |
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