Cargando…
CALCOCO2/NDP52 initiates selective autophagy through recruitment of ULK and TBK1 kinase complexes
The selective macroautophagy of prospective cargo necessitates activity of the autophagy machinery at cargo-determined locations. Whether phagophore membranes are recruited to, or are generated de novo at, the cargo is unknown. In our recent study we show that damaged Salmonella-containing vacuoles,...
Autores principales: | Boyle, Keith B., Ravenhill, Benjamin J., Randow, Felix |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693467/ https://www.ncbi.nlm.nih.gov/pubmed/31258038 http://dx.doi.org/10.1080/15548627.2019.1628548 |
Ejemplares similares
-
The Cargo Receptor NDP52 Initiates Selective Autophagy by Recruiting the ULK Complex to Cytosol-Invading Bacteria
por: Ravenhill, Benjamin J., et al.
Publicado: (2019) -
Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy
por: Vargas, Jose Norberto S., et al.
Publicado: (2019) -
Structural and biochemical advances on the recruitment of the autophagy-initiating ULK and TBK1 complexes by autophagy receptor NDP52
por: Fu, Tao, et al.
Publicado: (2021) -
Kaposi’s sarcoma-associated herpesvirus (KSHV) utilizes the NDP52/CALCOCO2 selective autophagy receptor to disassemble processing bodies
por: Robinson, Carolyn-Ann, et al.
Publicado: (2023) -
LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy
por: von Muhlinen, Natalia, et al.
Publicado: (2012)