Controversy Surrounding the Function of SpiC Protein in Salmonella: An Overview

Salmonella is an important pathogenic microorganism that can infect humans and animals and has been studied globally as a model microorganism for its pathogenesis. The SpiC protein of T3SS2 is a significant factor that has been studied for almost 20 years, but to date, the function/effect of SpiC in...

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Detalles Bibliográficos
Autores principales: Wang, Yaonan, Cai, Yuan, Zhang, Jian, Liu, Dong, Gong, Xiao, Pan, Zhiming, Geng, Shizhong, Jiao, Xin’an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693482/
https://www.ncbi.nlm.nih.gov/pubmed/31440219
http://dx.doi.org/10.3389/fmicb.2019.01784
Descripción
Sumario:Salmonella is an important pathogenic microorganism that can infect humans and animals and has been studied globally as a model microorganism for its pathogenesis. The SpiC protein of T3SS2 is a significant factor that has been studied for almost 20 years, but to date, the function/effect of SpiC in the pathogenesis of Salmonella has not been completely understood. There is controversy over the functions of SpiC protein in the literature. Thus, an overview of the literature on SpiC protein is provided here which highlights expression features of SpiC protein and its various functions and effect.

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