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Structure of Heteropentameric GABA(A) Receptors and Receptor-Anchoring Properties of Gephyrin
γ-Aminobutyric acid type A receptors (GABA(A)Rs) mediate the majority of fast synaptic inhibition in the central nervous system (CNS). GABA(A)Rs belong to the Cys-loop superfamily of pentameric ligand-gated ion channels (pLGIC) and are assembled from 19 different subunits. As dysfunctional GABAergic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693554/ https://www.ncbi.nlm.nih.gov/pubmed/31440140 http://dx.doi.org/10.3389/fnmol.2019.00191 |