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Structure of Heteropentameric GABA(A) Receptors and Receptor-Anchoring Properties of Gephyrin

γ-Aminobutyric acid type A receptors (GABA(A)Rs) mediate the majority of fast synaptic inhibition in the central nervous system (CNS). GABA(A)Rs belong to the Cys-loop superfamily of pentameric ligand-gated ion channels (pLGIC) and are assembled from 19 different subunits. As dysfunctional GABAergic...

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Detalles Bibliográficos
Autores principales: Kasaragod, Vikram Babu, Schindelin, Hermann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693554/
https://www.ncbi.nlm.nih.gov/pubmed/31440140
http://dx.doi.org/10.3389/fnmol.2019.00191