Cargando…
Triazoloquinazolines as a new class of potent α-glucosidase inhibitors: in vitro evaluation and docking study
Previously, we synthesized triazoloquinazolines 1–14 and characterized their structure. In this study, we aimed to evaluate the in vitro activity of the targets 1–14 as α-glucosidase inhibitors using α-glucosidase enzyme from Saccharomyces cerevisiae type 1. Among the tested compounds, triazoloquina...
Autores principales: | Abuelizz, Hatem A., Anouar, El Hassane, Ahmad, Rohaya, Azman, Nor Izzati Iwana Nor, Marzouk, Mohamed, Al-Salahi, Rashad |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693780/ https://www.ncbi.nlm.nih.gov/pubmed/31412050 http://dx.doi.org/10.1371/journal.pone.0220379 |
Ejemplares similares
-
Synthesis, biological activity and molecular docking of new tricyclic series as α-glucosidase inhibitors
por: Abuelizz, Hatem A., et al.
Publicado: (2019) -
Investigation the antioxidant activity of benzo[g]triazoloquinazolines correlated with a DFT study
por: Almehizia, Abdulrahman A., et al.
Publicado: (2019) -
Cytotoxicity and Anti-Inflammatory Activity of Methylsulfanyl-triazoloquinazolines
por: Al-Salahi, Rashad A., et al.
Publicado: (2013) -
Molecular Docking and Anticonvulsant Activity of Newly Synthesized Quinazoline Derivatives
por: Abuelizz, Hatem A., et al.
Publicado: (2017) -
Investigation of some benzoquinazoline and quinazoline derivatives as novel inhibitors of HCV-NS3/4A protease: biological, molecular docking and QSAR studies
por: Abuelizz, Hatem A., et al.
Publicado: (2020)