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Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart

Collagen production in the adult heart is thought to be regulated by the fibroblast, although cardiomyocytes and endothelial cells also express multiple collagen mRNAs. Molecular chaperones are required for procollagen biosynthesis, including heat shock protein 47 (Hsp47). To determine the cell type...

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Detalles Bibliográficos
Autores principales:	Khalil, Hadi, Kanisicak, Onur, Vagnozzi, Ronald J., Johansen, Anne Katrine, Maliken, Bryan D., Prasad, Vikram, Boyer, Justin G., Brody, Matthew J., Schips, Tobias, Kilian, Katja K., Correll, Robert N., Kawasaki, Kunito, Nagata, Kazuhiro, Molkentin, Jeffery D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693833/ https://www.ncbi.nlm.nih.gov/pubmed/31393098 http://dx.doi.org/10.1172/jci.insight.128722

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