ORC-13661 protects sensory hair cells from aminoglycoside and cisplatin ototoxicity

Aminoglycoside (AG) antibiotics are widely used to prevent life-threatening infections, and cisplatin is used in the treatment of various cancers, but both are ototoxic and result in loss of sensory hair cells from the inner ear. ORC-13661 is a new drug that was derived from PROTO-1, a compound firs...

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Detalles Bibliográficos
Autores principales: Kitcher, Siân R., Kirkwood, Nerissa K., Camci, Esra D., Wu, Patricia, Gibson, Robin M., Redila, Van A., Simon, Julian A., Rubel, Edwin W., Raible, David W., Richardson, Guy P., Kros, Corné J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693895/
https://www.ncbi.nlm.nih.gov/pubmed/31391343
http://dx.doi.org/10.1172/jci.insight.126764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693895/
https://www.ncbi.nlm.nih.gov/pubmed/31391343
http://dx.doi.org/10.1172/jci.insight.126764

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