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Functional protein dynamics on uncharted time scales detected by nanoparticle-assisted NMR spin relaxation

Protein function depends critically on intrinsic internal dynamics, which is manifested in distinct ways, such as loop motions that regulate protein recognition and catalysis. Under physiological conditions, dynamic processes occur on a wide range of time scales from subpicoseconds to seconds. Commo...

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Detalles Bibliográficos
Autores principales: Xie, Mouzhe, Yu, Lei, Bruschweiler-Li, Lei, Xiang, Xinyao, Hansen, Alexandar L., Brüschweiler, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693908/
https://www.ncbi.nlm.nih.gov/pubmed/31453342
http://dx.doi.org/10.1126/sciadv.aax5560

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