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Functional protein dynamics on uncharted time scales detected by nanoparticle-assisted NMR spin relaxation
Protein function depends critically on intrinsic internal dynamics, which is manifested in distinct ways, such as loop motions that regulate protein recognition and catalysis. Under physiological conditions, dynamic processes occur on a wide range of time scales from subpicoseconds to seconds. Commo...
Autores principales: | Xie, Mouzhe, Yu, Lei, Bruschweiler-Li, Lei, Xiang, Xinyao, Hansen, Alexandar L., Brüschweiler, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693908/ https://www.ncbi.nlm.nih.gov/pubmed/31453342 http://dx.doi.org/10.1126/sciadv.aax5560 |
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