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Inhaled GM-CSF in neonatal mice provides durable protection against bacterial pneumonia

Pneumonia poses profound health threats to preterm infants. Alveolar macrophages (AMs) eliminate inhaled pathogens while maintaining surfactant homeostasis. As AM development only occurs perinatally, therapies that accelerate AM maturation in preterms may improve outcomes. We tested therapeutic resc...

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Detalles Bibliográficos
Autores principales: Todd, Elizabeth M., Ramani, Rashmi, Szasz, Taylor P., Morley, S. Celeste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693910/
https://www.ncbi.nlm.nih.gov/pubmed/31453341
http://dx.doi.org/10.1126/sciadv.aax3387

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