The Human-Specific and Smooth Muscle Cell-Enriched LncRNA SMILR Promotes Proliferation by Regulating Mitotic CENPF mRNA and Drives Cell-Cycle Progression Which Can Be Targeted to Limit Vascular Remodeling

RATIONALE: In response to blood vessel wall injury, aberrant proliferation of vascular smooth muscle cells (SMCs) causes pathological remodeling. However, the controlling mechanisms are not completely understood. OBJECTIVE: We recently showed that the human long noncoding RNA, SMILR, promotes vascul...

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Detalles Bibliográficos
Autores principales: Mahmoud, Amira D., Ballantyne, Margaret D., Miscianinov, Vladislav, Pinel, Karine, Hung, John, Scanlon, Jessica P., Iyinikkel, Jean, Kaczynski, Jakub, Tavares, Adriana S., Bradshaw, Angela C., Mills, Nicholas L., Newby, David E., Caporali, Andrea, Gould, Gwyn W., George, Sarah J., Ulitsky, Igor, Sluimer, Judith C., Rodor, Julie, Baker, Andrew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693924/
https://www.ncbi.nlm.nih.gov/pubmed/31339449
http://dx.doi.org/10.1161/CIRCRESAHA.119.314876

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