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An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters

Anaerobic bacteria represent an overlooked rich source of biological and chemical diversity. Due to the challenge of cultivation and genetic intractability, assessing the capability of their biosynthetic gene clusters (BGCs) for secondary metabolite production requires an efficient heterologous expr...

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Detalles Bibliográficos
Autores principales: Hao, Tingting, Xie, Zhoujie, Wang, Min, Liu, Liwei, Zhang, Yuwei, Wang, Weicang, Zhang, Zhao, Zhao, Xuejin, Li, Pengwei, Guo, Zhengyan, Gao, Shushan, Lou, Chunbo, Zhang, Guodong, Merritt, Justin, Horsman, Geoff P., Chen, Yihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694145/
https://www.ncbi.nlm.nih.gov/pubmed/31413323
http://dx.doi.org/10.1038/s41467-019-11673-0