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An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters
Anaerobic bacteria represent an overlooked rich source of biological and chemical diversity. Due to the challenge of cultivation and genetic intractability, assessing the capability of their biosynthetic gene clusters (BGCs) for secondary metabolite production requires an efficient heterologous expr...
Autores principales: | Hao, Tingting, Xie, Zhoujie, Wang, Min, Liu, Liwei, Zhang, Yuwei, Wang, Weicang, Zhang, Zhao, Zhao, Xuejin, Li, Pengwei, Guo, Zhengyan, Gao, Shushan, Lou, Chunbo, Zhang, Guodong, Merritt, Justin, Horsman, Geoff P., Chen, Yihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694145/ https://www.ncbi.nlm.nih.gov/pubmed/31413323 http://dx.doi.org/10.1038/s41467-019-11673-0 |
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