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The POU4F2/Brn-3b transcription factor is required for the hypertrophic response to angiotensin II in the heart
Adult hearts respond to increased workload such as prolonged stress or injury, by undergoing hypertrophic growth. During this process, the early adaptive responses are important for maintaining cardiac output whereas at later stages, pathological responses such as cardiomyocyte apoptosis and fibrosi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694165/ https://www.ncbi.nlm.nih.gov/pubmed/31413277 http://dx.doi.org/10.1038/s41419-019-1848-y |