The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells

Most of over a thousand mitochondrial proteins are encoded by nuclear genes and must be imported from the cytosol. Little is known about the cytosolic events regulating mitochondrial protein import, partly due to the lack of appropriate tools for its assessment in living cells. We engineered an indu...

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Detalles Bibliográficos
Autores principales: Jacoupy, M., Hamon-Keromen, E., Ordureau, A., Erpapazoglou, Z., Coge, F., Corvol, J.-C., Nosjean, O., Mannoury la Cour, C., Millan, M. J., Boutin, J. A., Harper, J. W., Brice, A., Guedin, D., Gautier, C. A., Corti, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694185/
https://www.ncbi.nlm.nih.gov/pubmed/31413265
http://dx.doi.org/10.1038/s41598-019-47352-9

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