Screening inducers of neuronal BDNF gene transcription using primary cortical cell cultures from BDNF-luciferase transgenic mice

Brain-derived neurotrophic factor (BDNF) is a key player in synaptic plasticity, and consequently, learning and memory. Because of its fundamental role in numerous neurological functions in the central nervous system, BDNF has utility as a biomarker and drug target for neurodegenerative and neuropsy...

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Detalles Bibliográficos
Autores principales: Fukuchi, Mamoru, Okuno, Yui, Nakayama, Hironori, Nakano, Aoi, Mori, Hisashi, Mitazaki, Satoru, Nakano, Yuka, Toume, Kazufumi, Jo, Michiko, Takasaki, Ichiro, Watanabe, Kazuki, Shibahara, Naotoshi, Komatsu, Katsuko, Tabuchi, Akiko, Tsuda, Masaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694194/
https://www.ncbi.nlm.nih.gov/pubmed/31413298
http://dx.doi.org/10.1038/s41598-019-48361-4

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