Mouse Model of Congenital Heart Defects, Dysmorphic Facial Features and Intellectual Developmental Disorders as a Result of Non-functional CDK13

Congenital heart defects, dysmorphic facial features and intellectual developmental disorders (CHDFIDD) syndrome in humans was recently associated with mutation in CDK13 gene. In order to assess the loss of function of Cdk13 during mouse development, we employed gene trap knock-out (KO) allele in Cd...

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Detalles Bibliográficos
Autores principales: Nováková, Monika, Hampl, Marek, Vrábel, Dávid, Procházka, Jan, Petrezselyová, Silvia, Procházková, Michaela, Sedláček, Radislav, Kavková, Michaela, Zikmund, Tomáš, Kaiser, Jozef, Juan, Hsien-Chia, Fann, Ming-Ji, Buchtová, Marcela, Kohoutek, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694211/
https://www.ncbi.nlm.nih.gov/pubmed/31440507
http://dx.doi.org/10.3389/fcell.2019.00155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694211/
https://www.ncbi.nlm.nih.gov/pubmed/31440507
http://dx.doi.org/10.3389/fcell.2019.00155

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