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The Precursor to Glutathione (GSH), γ-Glutamylcysteine (GGC), Can Ameliorate Oxidative Damage and Neuroinflammation Induced by Aβ(40) Oligomers in Human Astrocytes

Glutathione (GSH) is one of the most abundant thiol antioxidants in cells. Many chronic and age-related diseases are associated with a decline in cellular GSH levels or impairment in the catalytic activity of the GSH biosynthetic enzyme glutamate cysteine ligase (GCL). γ-glutamylcysteine (GGC), a pr...

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Detalles Bibliográficos
Autores principales:	Braidy, Nady, Zarka, Martin, Jugder, Bat-Erdene, Welch, Jeffrey, Jayasena, Tharusha, Chan, Daniel K. Y., Sachdev, Perminder, Bridge, Wallace
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694290/ https://www.ncbi.nlm.nih.gov/pubmed/31440155 http://dx.doi.org/10.3389/fnagi.2019.00177

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