Phase separation of 53BP1 determines liquid‐like behavior of DNA repair compartments

The DNA damage response (DDR) generates transient repair compartments to concentrate repair proteins and activate signaling factors. The physicochemical properties of these spatially confined compartments and their function remain poorly understood. Here, we establish, based on live cell microscopy...

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Detalles Bibliográficos
Autores principales: Kilic, Sinan, Lezaja, Aleksandra, Gatti, Marco, Bianco, Eliana, Michelena, Jone, Imhof, Ralph, Altmeyer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694294/
https://www.ncbi.nlm.nih.gov/pubmed/31267591
http://dx.doi.org/10.15252/embj.2018101379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694294/
https://www.ncbi.nlm.nih.gov/pubmed/31267591
http://dx.doi.org/10.15252/embj.2018101379

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