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Phase separation of 53BP1 determines liquid‐like behavior of DNA repair compartments
The DNA damage response (DDR) generates transient repair compartments to concentrate repair proteins and activate signaling factors. The physicochemical properties of these spatially confined compartments and their function remain poorly understood. Here, we establish, based on live cell microscopy...
Autores principales: | Kilic, Sinan, Lezaja, Aleksandra, Gatti, Marco, Bianco, Eliana, Michelena, Jone, Imhof, Ralph, Altmeyer, Matthias |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694294/ https://www.ncbi.nlm.nih.gov/pubmed/31267591 http://dx.doi.org/10.15252/embj.2018101379 |
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