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Temporal integration of mitochondrial stress signals by the PINK1:Parkin pathway

BACKGROUND: The PINK1:Parkin pathway regulates the autophagic removal of damaged and dysfunctional mitochondria. While the response of this pathway to complete loss of ΔΨm, as caused by high concentrations of mitochondrial ionophores, has been well characterized, it remains unclear how the pathway m...

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Detalles Bibliográficos
Autores principales: Bowling, J. Logan, Skolfield, Mary Catherine, Riley, Wesley A., Nolin, Andrew P., Wolf, Larissa C., Nelson, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694515/
https://www.ncbi.nlm.nih.gov/pubmed/31412778
http://dx.doi.org/10.1186/s12860-019-0220-5