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Temporal integration of mitochondrial stress signals by the PINK1:Parkin pathway
BACKGROUND: The PINK1:Parkin pathway regulates the autophagic removal of damaged and dysfunctional mitochondria. While the response of this pathway to complete loss of ΔΨm, as caused by high concentrations of mitochondrial ionophores, has been well characterized, it remains unclear how the pathway m...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694515/ https://www.ncbi.nlm.nih.gov/pubmed/31412778 http://dx.doi.org/10.1186/s12860-019-0220-5 |