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Restoration of primary cilia in obese adipose-derived mesenchymal stem cells by inhibiting Aurora A or extracellular signal-regulated kinase

BACKGROUND: Obesity impairs a variety of cell types including adipose-derived mesenchymal stem cells (ASCs). ASCs are indispensable for tissue homeostasis/repair, immunomodulation, and cell renewal. It has been demonstrated that obese ASCs are defective in differentiation, motility, immunomodulation...

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Detalles Bibliográficos
Autores principales:	Ritter, Andreas, Kreis, Nina-Naomi, Roth, Susanne, Friemel, Alexandra, Jennewein, Lukas, Eichbaum, Christine, Solbach, Christine, Louwen, Frank, Yuan, Juping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694567/ https://www.ncbi.nlm.nih.gov/pubmed/31412932 http://dx.doi.org/10.1186/s13287-019-1373-z

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