Cargando…

Transplantation of adipose-derived stem cells overexpressing inducible nitric oxide synthase ameliorates diabetes mellitus-induced erectile dysfunction in rats

BACKGROUND: Erectile dysfunction is a major complication of diabetes mellitus. Adipose-derived stem cells (ADSCs) have attracted much attention as a promising tool for the treatment of diabetes mellitus-induced erectile dysfunction (DMED). Inducible nitric oxide synthase (iNOS) plays an important ro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yan, Yang, Jun, Zhuan, Li, Zang, Guanghui, Wang, Tao, Liu, Jihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2019
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694783/ https://www.ncbi.nlm.nih.gov/pubmed/31423366 http://dx.doi.org/10.7717/peerj.7507

Ejemplares similares

Icariside II induces rapid phosphorylation of endothelial nitric oxide synthase via multiple signaling pathways
por: Song, Wenpeng, et al.
Publicado: (2022)

Engineered Adipose-Derived Stem Cells Overexpressing RXFP1 via CRISPR Activation Ameliorate Erectile Dysfunction in Diabetic Rats
por: Sun, Taotao, et al.
Publicado: (2023)

Association of endothelial nitric oxide synthase polymorphisms with an increased risk of erectile dysfunction
por: Gao, Lei, et al.
Publicado: (2017)

Endothelial nitric oxide synthase gene polymorphisms and erectile dysfunction in chronic pain
por: Segura, Ana, et al.
Publicado: (2019)

Non-Coding RNAs: New Dawn for Diabetes Mellitus Induced Erectile Dysfunction
por: Xu, Wenchao, et al.
Publicado: (2022)

Screening and identification of NOTCH1, CDKN2A, and NOS3 as differentially expressed autophagy-related genes in erectile dysfunction
por: Luo, Chao, et al.
Publicado: (2021)

GPX4 Alleviates Diabetes Mellitus-Induced Erectile Dysfunction by Inhibiting Ferroptosis
por: Xu, Wenchao, et al.
Publicado: (2022)

Hyperhomocysteinaemia in rats is associated with erectile dysfunction by impairing endothelial nitric oxide synthase activity
por: Jiang, Weijun, et al.
Publicado: (2016)

MiR-190 ameliorates glucotoxicity-induced dysfunction and apoptosis of pancreatic β-cells by inhibiting NOX2-mediated reactive oxygen species production
por: Lu, Huinan, et al.
Publicado: (2022)

Glucosylceramide synthase regulates hepatocyte repair after concanavalin A-induced immune-mediated liver injury
por: Gan, Jian, et al.
Publicado: (2021)

The role of autophagy in high-fat diet-induced insulin resistance of adipose tissues in mice
por: Budi, Yovita Permata, et al.
Publicado: (2022)

Phenotype of Transgenic Mice Overexpressed with Inducible Nitric Oxide Synthase in the Retina
por: Wu, Guey Shuang, et al.
Publicado: (2012)

Overexpression of Inducible Nitric Oxide Synthase in Allergic and Nonallergic Nasal Polyp
por: Sadek, Ahmed Adel, et al.
Publicado: (2019)

Rutin ameliorates carbon tetrachloride (CCl(4))-induced hepatorenal toxicity and hypogonadism in male rats
por: Elsawy, Hany, et al.
Publicado: (2019)

Ameliorative effect of apelin-13 against renal complications in L-NAME-induced preeclampsia in rats
por: Hamza, Reham Z., et al.
Publicado: (2021)

Chronic unpredictable mild stress promotes atherosclerosis via adipose tissue dysfunction in ApoE(-/-) mice
por: Mao, Min, et al.
Publicado: (2023)

Ferroptosis is involved in corpus cavernosum smooth muscle cells impairment in diabetes mellitus‐induced erectile dysfunction
por: Xu, Wenchao, et al.
Publicado: (2022)

Liraglutide Ameliorates Erectile Dysfunction via Regulating Oxidative Stress, the RhoA/ROCK Pathway and Autophagy in Diabetes Mellitus
por: Yuan, Penghui, et al.
Publicado: (2020)

Human umbilical cord mesenchymal stem cells ameliorate erectile dysfunction in rats with diabetes mellitus through the attenuation of ferroptosis
por: Feng, Huan, et al.
Publicado: (2022)

Comparison of characteristics between Chinese diabetes mellitus-induced erectile dysfunction populations and non-diabetes mellitus-induced erectile dysfunction populations: A cross-sectional study
por: Peng, Jingxuan, et al.
Publicado: (2022)

Retinal dysfunction induced in a mouse model of unilateral common carotid artery occlusion
por: Lee, Deokho, et al.
Publicado: (2021)

Chronic liver diseases and erectile dysfunction
por: Zang, Guanghui, et al.
Publicado: (2023)

Validation of Plasmodium falciparum deoxyhypusine synthase as an antimalarial target
por: Aroonsri, Aiyada, et al.
Publicado: (2019)

AB197. Endothelial nitric oxide synthase polymorphism and erectile dysfunction risk: evidence based on a meta-analysis
por: Zhang, Zheng, et al.
Publicado: (2015)

Identification of MOS9 as an interaction partner for chalcone synthase in the nucleus
por: Watkinson, Jonathan I., et al.
Publicado: (2018)

Ganoderma lucidum polysaccharide ameliorated diabetes mellitus-induced erectile dysfunction in rats by regulating fibrosis and the NOS/ERK/JNK pathway
por: Yao, Xiaolin, et al.
Publicado: (2022)

Exosomes derived from plasma: promising immunomodulatory agents for promoting angiogenesis to treat radiation-induced vascular dysfunction
por: Li, Yanxi, et al.
Publicado: (2021)

Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM
por: Zhou, Anna, et al.
Publicado: (2015)

Purification and biochemical characterization of recombinant Persicaria minor β-sesquiphellandrene synthase
por: Ker, De-Sheng, et al.
Publicado: (2017)

Advances in physical diagnosis and treatment of male erectile dysfunction
por: Pang, Kun, et al.
Publicado: (2023)

Erectile dysfunction and exosome therapy
por: Feng, Huan, et al.
Publicado: (2023)

Phlorizin Exerts Direct Protective Effects on Palmitic Acid (PA)-Induced Endothelial Dysfunction by Activating the PI3K/AKT/eNOS Signaling Pathway and Increasing the Levels of Nitric Oxide (NO)
por: Li, Chun-Ying, et al.
Publicado: (2018)

Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase
por: Zhang, Yan, et al.
Publicado: (2016)

Long-term administration of ketamine induces erectile dysfunction by decreasing neuronal nitric oxide synthase on cavernous nerve and increasing corporal smooth muscle cell apoptosis in rats
por: Shang, Hung-Sheng, et al.
Publicado: (2016)

Mechanisms of Diesel-Induced Endothelial Nitric Oxide Synthase Dysfunction in Coronary Arterioles
por: Cherng, Tom W., et al.
Publicado: (2011)

Neuronal Nitric Oxide Synthase-Dependent Amelioration of Diastolic Dysfunction in Rats with Chronic Renocardiac Syndrome
por: Bongartz, Lennart G., et al.
Publicado: (2015)

The stress-responsive kinases MAPKAPK2/MAPKAPK3 activate starvation-induced autophagy through Beclin 1 phosphorylation
por: Wei, Yongjie, et al.
Publicado: (2015)

Exosomes derived from smooth muscle cells ameliorate diabetes‐induced erectile dysfunction by inhibiting fibrosis and modulating the NO/cGMP pathway
por: Song, Jingyu, et al.
Publicado: (2020)

Transient expression and purification of β-caryophyllene synthase in Nicotiana benthamiana to produce β-caryophyllene in vitro
por: Muthusamy, Saraladevi, et al.
Publicado: (2020)

Mycophenolate suppresses inflammation by inhibiting prostaglandin synthases: a study of molecular and experimental drug repurposing
por: Al-Hizab, Fahad, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_oahl8ff330dldfgv8rj8lmd1vt