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AGER-Mediated Lipid Peroxidation Drives Caspase-11 Inflammasome Activation in Sepsis
Inflammasome activation can trigger an inflammatory and innate immune response through the release of cytokines and induction of pyroptosis. A dysfunctional inflammasome has been implicated in the development of human pathologies, including sepsis and septic shock. Here, we show that advanced glycos...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694796/ https://www.ncbi.nlm.nih.gov/pubmed/31440260 http://dx.doi.org/10.3389/fimmu.2019.01904 |