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Progeny Varicella-Zoster Virus Capsids Exit the Nucleus but Never Undergo Secondary Envelopment during Autophagic Flux Inhibition by Bafilomycin A1

Varicella-zoster virus (VZV) is an alphaherpesvirus that lacks the herpesviral neurovirulence protein ICP34.5. The underlying hypothesis of this project was that inhibitors of autophagy reduce VZV infectivity. We selected the vacuolar proton ATPase inhibitor bafilomycin A1 for analysis because of it...

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Detalles Bibliográficos
Autores principales:	Girsch, James H., Walters, Katherine, Jackson, Wallen, Grose, Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Structure and Assembly
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694825/ https://www.ncbi.nlm.nih.gov/pubmed/31217243 http://dx.doi.org/10.1128/JVI.00505-19

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