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Development of type 2 diabetes mellitus after gestational diabetes in a cohort in KSA: Prevalence and risk factors
OBJECTIVES: KSA has the highest prevalence of diabetes mellitus among Middle Eastern countries with a prevalence range of 21%–24%. Gestational diabetes (GDM) is a well-known risk factor for type 2 diabetes mellitus (T2DM). GDM is associated with a 7-fold increased risk of T2DM. Thus, this research a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taibah University
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695016/ https://www.ncbi.nlm.nih.gov/pubmed/31435382 http://dx.doi.org/10.1016/j.jtumed.2018.11.004 |
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author | Mahzari, Moeber M. Alwadi, Fahad A. Alhussain, Basil M. Alenzi, Tariq M. Omair, Aamir A. Al Dera, Hussain S. |
author_facet | Mahzari, Moeber M. Alwadi, Fahad A. Alhussain, Basil M. Alenzi, Tariq M. Omair, Aamir A. Al Dera, Hussain S. |
author_sort | Mahzari, Moeber M. |
collection | PubMed |
description | OBJECTIVES: KSA has the highest prevalence of diabetes mellitus among Middle Eastern countries with a prevalence range of 21%–24%. Gestational diabetes (GDM) is a well-known risk factor for type 2 diabetes mellitus (T2DM). GDM is associated with a 7-fold increased risk of T2DM. Thus, this research assessed the prevalence and risk factors associated with the development T2DM in a cohort of patients with GDM in KSA. METHODS: The medical records of patients with GDM who visited the outpatient clinics of a tertiary care hospital from 2011 to 2014 were included in this study. Patients with a prior diagnosis of diabetes mellitus before pregnancy and those with GDM who did not have postpartum diabetes screening were excluded. RESULTS: A total of 123 women with GDM and underwent postpartum diabetes screening, 82 (67%) developed T2DM based on follow-up records. Approximately 45% (37/82) of patients who developed T2DM were screened ≤6 months after delivery, whereas 55%(45/82) were screened >6 months after delivery. Older patients, patients who had a higher number of pregnancies (gravidity and parity), and patients with previous GDM were more likely to develop T2DM. CONCLUSION: In KSA, women who developed GDM, particularly those who are older, multigravid, and multiparous and who have a prior history of GDM, are at an increased risk of developing T2DM. Postpartum diabetes screening of patients with GDM within the recommended period need to be improved. |
format | Online Article Text |
id | pubmed-6695016 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Taibah University |
record_format | MEDLINE/PubMed |
spelling | pubmed-66950162019-08-21 Development of type 2 diabetes mellitus after gestational diabetes in a cohort in KSA: Prevalence and risk factors Mahzari, Moeber M. Alwadi, Fahad A. Alhussain, Basil M. Alenzi, Tariq M. Omair, Aamir A. Al Dera, Hussain S. J Taibah Univ Med Sci Brief Communication OBJECTIVES: KSA has the highest prevalence of diabetes mellitus among Middle Eastern countries with a prevalence range of 21%–24%. Gestational diabetes (GDM) is a well-known risk factor for type 2 diabetes mellitus (T2DM). GDM is associated with a 7-fold increased risk of T2DM. Thus, this research assessed the prevalence and risk factors associated with the development T2DM in a cohort of patients with GDM in KSA. METHODS: The medical records of patients with GDM who visited the outpatient clinics of a tertiary care hospital from 2011 to 2014 were included in this study. Patients with a prior diagnosis of diabetes mellitus before pregnancy and those with GDM who did not have postpartum diabetes screening were excluded. RESULTS: A total of 123 women with GDM and underwent postpartum diabetes screening, 82 (67%) developed T2DM based on follow-up records. Approximately 45% (37/82) of patients who developed T2DM were screened ≤6 months after delivery, whereas 55%(45/82) were screened >6 months after delivery. Older patients, patients who had a higher number of pregnancies (gravidity and parity), and patients with previous GDM were more likely to develop T2DM. CONCLUSION: In KSA, women who developed GDM, particularly those who are older, multigravid, and multiparous and who have a prior history of GDM, are at an increased risk of developing T2DM. Postpartum diabetes screening of patients with GDM within the recommended period need to be improved. Taibah University 2018-12-07 /pmc/articles/PMC6695016/ /pubmed/31435382 http://dx.doi.org/10.1016/j.jtumed.2018.11.004 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Brief Communication Mahzari, Moeber M. Alwadi, Fahad A. Alhussain, Basil M. Alenzi, Tariq M. Omair, Aamir A. Al Dera, Hussain S. Development of type 2 diabetes mellitus after gestational diabetes in a cohort in KSA: Prevalence and risk factors |
title | Development of type 2 diabetes mellitus after gestational diabetes in a cohort in KSA: Prevalence and risk factors |
title_full | Development of type 2 diabetes mellitus after gestational diabetes in a cohort in KSA: Prevalence and risk factors |
title_fullStr | Development of type 2 diabetes mellitus after gestational diabetes in a cohort in KSA: Prevalence and risk factors |
title_full_unstemmed | Development of type 2 diabetes mellitus after gestational diabetes in a cohort in KSA: Prevalence and risk factors |
title_short | Development of type 2 diabetes mellitus after gestational diabetes in a cohort in KSA: Prevalence and risk factors |
title_sort | development of type 2 diabetes mellitus after gestational diabetes in a cohort in ksa: prevalence and risk factors |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695016/ https://www.ncbi.nlm.nih.gov/pubmed/31435382 http://dx.doi.org/10.1016/j.jtumed.2018.11.004 |
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