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Universal principles of membrane protein assembly, composition and evolution

Structural diversity in α-helical membrane proteins (MP) arises from variations in helix-helix crossings and contacts that may bias amino acid usage. Here, we reveal systematic changes in transmembrane amino acid frequencies (f) as a function of the number of helices (n). For eukarya, breaks in f(n)...

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Detalles Bibliográficos
Autores principales: Situ, Alan J., Ulmer, Tobias S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695178/
https://www.ncbi.nlm.nih.gov/pubmed/31415673
http://dx.doi.org/10.1371/journal.pone.0221372