Cargando…

Investigation of base excision repair gene variants in late-onset Alzheimer’s disease

Base excision repair (BER) defects and concomitant oxidative DNA damage accumulation play a role in the etiology and progression of late-onset Alzheimer’s disease (LOAD). However, it is not known whether genetic variant(s) of specific BER genes contribute to reduced BER activity in LOAD patients and...

Descripción completa

Detalles Bibliográficos
Autores principales: Ertuzun, Tugce, Semerci, Asli, Cakir, Mehmet Emin, Ekmekcioglu, Aysegul, Gok, Mehmet Oguz, Soltys, Daniela T., de Souza-Pinto, Nadja C., Sezerman, Ugur, Muftuoglu, Meltem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695184/
https://www.ncbi.nlm.nih.gov/pubmed/31415677
http://dx.doi.org/10.1371/journal.pone.0221362