The alpha-1 subunit of the Na(+),K(+)-ATPase (ATP1A1) is required for macropinocytic entry of respiratory syncytial virus (RSV) in human respiratory epithelial cells

Human respiratory syncytial virus (RSV) is the leading viral cause of acute pediatric lower respiratory tract infections worldwide, with no available vaccine or effective antiviral drug. To gain insight into virus-host interactions, we performed a genome-wide siRNA screen. The expression of over 20,...

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Detalles Bibliográficos
Autores principales: Lingemann, Matthias, McCarty, Thomas, Liu, Xueqiao, Buchholz, Ursula J., Surman, Sonja, Martin, Scott E., Collins, Peter L., Munir, Shirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695199/
https://www.ncbi.nlm.nih.gov/pubmed/31381610
http://dx.doi.org/10.1371/journal.ppat.1007963

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