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NS2B/NS3 mutations enhance the infectivity of genotype I Japanese encephalitis virus in amplifying hosts

Genotype I (GI) virus has replaced genotype III (GIII) virus as the dominant Japanese encephalitis virus (JEV) in the epidemic area of Asia. The mechanism underlying the genotype replacement remains unclear. Therefore, we focused our current study on investigating the roles of mosquito vector and am...

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Detalles Bibliográficos
Autores principales: Fan, Yi-Chin, Liang, Jian-Jong, Chen, Jo-Mei, Lin, Jen-Wei, Chen, Yi-Ying, Su, Kuan-Hsuan, Lin, Chang-Chi, Tu, Wu-Chun, Chiou, Ming-Tang, Ou, Shan-Chia, Chang, Gwong-Jen J., Lin, Yi-Ling, Chiou, Shyan-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695206/
https://www.ncbi.nlm.nih.gov/pubmed/31381617
http://dx.doi.org/10.1371/journal.ppat.1007992