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Bipartite interface of the measles virus phosphoprotein X domain with the large polymerase protein regulates viral polymerase dynamics

Measles virus (MeV) is a highly contagious, re-emerging, major human pathogen. Replication requires a viral RNA-dependent RNA polymerase (RdRP) consisting of the large (L) polymerase protein complexed with the homo-tetrameric phosphoprotein (P). In addition, P mediates interaction with the nucleopro...

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Detalles Bibliográficos
Autores principales: Du Pont, Venice, Jiang, Yi, Plemper, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695210/
https://www.ncbi.nlm.nih.gov/pubmed/31381607
http://dx.doi.org/10.1371/journal.ppat.1007995

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