Early Presentation of a Rare Complication of Sodium-Glucose Cotransporter-2 Inhibitors 10 Days After Initiation: Case Report and Literature Review

Fournier’s gangrene is an extremely rare infection that can occur in immunocompromised patients, especially those with diabetes. Given the severity of this infection and the new associated link to sodium-glucose cotransporter-2 inhibitors, the US FDA recently issued a warning in August 2018. Few cas...

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Autores principales: Elshimy, Ghada, Correa, Ricardo, Alsayed, Mahmoud, Jyothinagaram, Sathya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2019
Materias:
Endocrinology/Diabetes/Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695297/
https://www.ncbi.nlm.nih.gov/pubmed/31423402
http://dx.doi.org/10.7759/cureus.5173
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author Elshimy, Ghada
Correa, Ricardo
Alsayed, Mahmoud
Jyothinagaram, Sathya
author_facet Elshimy, Ghada
Correa, Ricardo
Alsayed, Mahmoud
Jyothinagaram, Sathya
author_sort Elshimy, Ghada
collection PubMed
description Fournier’s gangrene is an extremely rare infection that can occur in immunocompromised patients, especially those with diabetes. Given the severity of this infection and the new associated link to sodium-glucose cotransporter-2 inhibitors, the US FDA recently issued a warning in August 2018. Few cases of Fournier’s gangrene have been reported in the literature in diabetic patients taking these oral medications. We report a case of Fournier’s gangrene presenting 10 days after a patient with type 2 diabetes started empagliflozin therapy.
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spelling pubmed-66952972019-08-17 Early Presentation of a Rare Complication of Sodium-Glucose Cotransporter-2 Inhibitors 10 Days After Initiation: Case Report and Literature Review Elshimy, Ghada Correa, Ricardo Alsayed, Mahmoud Jyothinagaram, Sathya Cureus Endocrinology/Diabetes/Metabolism Fournier’s gangrene is an extremely rare infection that can occur in immunocompromised patients, especially those with diabetes. Given the severity of this infection and the new associated link to sodium-glucose cotransporter-2 inhibitors, the US FDA recently issued a warning in August 2018. Few cases of Fournier’s gangrene have been reported in the literature in diabetic patients taking these oral medications. We report a case of Fournier’s gangrene presenting 10 days after a patient with type 2 diabetes started empagliflozin therapy. Cureus 2019-07-19 /pmc/articles/PMC6695297/ /pubmed/31423402 http://dx.doi.org/10.7759/cureus.5173 Text en Copyright © 2019, Elshimy et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Elshimy, Ghada
Correa, Ricardo
Alsayed, Mahmoud
Jyothinagaram, Sathya
Early Presentation of a Rare Complication of Sodium-Glucose Cotransporter-2 Inhibitors 10 Days After Initiation: Case Report and Literature Review
title Early Presentation of a Rare Complication of Sodium-Glucose Cotransporter-2 Inhibitors 10 Days After Initiation: Case Report and Literature Review
title_full Early Presentation of a Rare Complication of Sodium-Glucose Cotransporter-2 Inhibitors 10 Days After Initiation: Case Report and Literature Review
title_fullStr Early Presentation of a Rare Complication of Sodium-Glucose Cotransporter-2 Inhibitors 10 Days After Initiation: Case Report and Literature Review
title_full_unstemmed Early Presentation of a Rare Complication of Sodium-Glucose Cotransporter-2 Inhibitors 10 Days After Initiation: Case Report and Literature Review
title_short Early Presentation of a Rare Complication of Sodium-Glucose Cotransporter-2 Inhibitors 10 Days After Initiation: Case Report and Literature Review
title_sort early presentation of a rare complication of sodium-glucose cotransporter-2 inhibitors 10 days after initiation: case report and literature review
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695297/
https://www.ncbi.nlm.nih.gov/pubmed/31423402
http://dx.doi.org/10.7759/cureus.5173
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