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Diversity of oligomerization in Drosophila semaphorins suggests a mechanism of functional fine-tuning

Semaphorin ligands and their plexin receptors are one of the major cell guidance factors that trigger localised changes in the cytoskeleton. Binding of semaphorin homodimer to plexin brings two plexins in close proximity which is a prerequisite for plexin signalling. This model appears to be too sim...

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Detalles Bibliográficos
Autores principales: Rozbesky, Daniel, Robinson, Ross A., Jain, Vitul, Renner, Max, Malinauskas, Tomas, Harlos, Karl, Siebold, Christian, Jones, E. Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695400/
https://www.ncbi.nlm.nih.gov/pubmed/31417095
http://dx.doi.org/10.1038/s41467-019-11683-y

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