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Serum and brain natural copper stable isotopes in a mouse model of Alzheimer’s disease

Alzheimer’s disease is associated with the production of Cu rich aβ fibrils. Because monitoring the changes in Cu level of organs has been proposed to follow the evolution of the disease, we analyzed the copper isotopic composition of serum and brain of APPswe/PSEN1dE9 transgenic mice, a model of Al...

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Detalles Bibliográficos
Autores principales: Moynier, Frédéric, Creech, John, Dallas, Jessica, Le Borgne, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695409/
https://www.ncbi.nlm.nih.gov/pubmed/31417103
http://dx.doi.org/10.1038/s41598-019-47790-5