Peptide translocation by the lysosomal ABC transporter TAPL is regulated by coupling efficiency and activation energy

The lysosomal polypeptide transporter TAPL belongs to the superfamily of ATP-binding cassette transporters. TAPL forms a homodimeric transport complex, which translocates oligo- and polypeptides into the lumen of lysosomes driven by ATP hydrolysis. Although the structure and the function of ABC tran...

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Detalles Bibliográficos
Autores principales: Bock, Christoph, Zollmann, Tina, Lindt, Katharina-Astrid, Tampé, Robert, Abele, Rupert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695453/
https://www.ncbi.nlm.nih.gov/pubmed/31417173
http://dx.doi.org/10.1038/s41598-019-48343-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695453/
https://www.ncbi.nlm.nih.gov/pubmed/31417173
http://dx.doi.org/10.1038/s41598-019-48343-6

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