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Peptide translocation by the lysosomal ABC transporter TAPL is regulated by coupling efficiency and activation energy
The lysosomal polypeptide transporter TAPL belongs to the superfamily of ATP-binding cassette transporters. TAPL forms a homodimeric transport complex, which translocates oligo- and polypeptides into the lumen of lysosomes driven by ATP hydrolysis. Although the structure and the function of ABC tran...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695453/ https://www.ncbi.nlm.nih.gov/pubmed/31417173 http://dx.doi.org/10.1038/s41598-019-48343-6 |