Aldosterone Jeopardizes Myocardial Insulin and β-Adrenergic Receptor Signaling via G Protein-Coupled Receptor Kinase 2

Hyperaldosteronism alters cardiac function, inducing adverse left ventricle (LV) remodeling either via increased fibrosis deposition, mitochondrial dysfunction, or both. These harmful effects are due, at least in part, to the activation of the G protein-coupled receptor kinase 2 (GRK2). In this cont...

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Detalles Bibliográficos
Autores principales: Cannavo, Alessandro, Marzano, Federica, Elia, Andrea, Liccardo, Daniela, Bencivenga, Leonardo, Gambino, Giuseppina, Perna, Claudia, Rapacciuolo, Antonio, Cittadini, Antonio, Ferrara, Nicola, Paolocci, Nazareno, Koch, Walter J., Rengo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695474/
https://www.ncbi.nlm.nih.gov/pubmed/31447681
http://dx.doi.org/10.3389/fphar.2019.00888

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