Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation

In mammals, ∼100 deubiquitinases act on ∼20,000 intracellular ubiquitination sites. Deubiquitinases are commonly regarded as constitutively active, with limited regulatory and targeting capacity. The BRCA1-A and BRISC complexes serve in DNA double-strand break repair and immune signaling and contain...

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Detalles Bibliográficos
Autores principales: Rabl, Julius, Bunker, Richard D., Schenk, Andreas D., Cavadini, Simone, Gill, Mark E., Abdulrahman, Wassim, Andrés-Pons, Amparo, Luijsterburg, Martijn S., Ibrahim, Adel F.M., Branigan, Emma, Aguirre, Jacob D., Marceau, Aimee H., Guérillon, Claire, Bouwmeester, Tewis, Hassiepen, Ulrich, Peters, Antoine H.F.M., Renatus, Martin, Gelman, Laurent, Rubin, Seth M., Mailand, Niels, van Attikum, Haico, Hay, Ronald T., Thomä, Nicolas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695476/
https://www.ncbi.nlm.nih.gov/pubmed/31253574
http://dx.doi.org/10.1016/j.molcel.2019.06.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695476/
https://www.ncbi.nlm.nih.gov/pubmed/31253574
http://dx.doi.org/10.1016/j.molcel.2019.06.002

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