Berberine improved experimental chronic colitis by regulating interferon-γ- and IL-17A-producing lamina propria CD4(+) T cells through AMPK activation

The herbal medicine berberine (BBR) has been recently shown to be an AMP-activated protein kinase (AMPK) productive activator with various properties that induce anti-inflammatory responses. We investigated the effects of BBR on the mechanisms of mucosal CD4(+)T cell activation in vitro and on the i...

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Detalles Bibliográficos
Autores principales: Takahara, Masahiro, Takaki, Akinobu, Hiraoka, Sakiko, Adachi, Takuya, Shimomura, Yasuyuki, Matsushita, Hiroshi, Nguyen, Tien Thi Thuy, Koike, Kazuko, Ikeda, Airi, Takashima, Shiho, Yamasaki, Yasushi, Inokuchi, Toshihiro, Kinugasa, Hideaki, Sugihara, Yusaku, Harada, Keita, Eikawa, Shingo, Morita, Hidetoshi, Udono, Heiichiro, Okada, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695484/
https://www.ncbi.nlm.nih.gov/pubmed/31417110
http://dx.doi.org/10.1038/s41598-019-48331-w

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