Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain

Modification with SUMO regulates many eukaryotic proteins. Down-regulation of sumoylated forms of proteins involves either their desumoylation, and hence recycling of the unmodified form, or their proteolytic targeting by ubiquitin ligases that recognize their SUMO modification (termed STUbL or ULS)...

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Detalles Bibliográficos
Autores principales: Sriramachandran, Annie M., Meyer-Teschendorf, Katrin, Pabst, Stefan, Ulrich, Helle D., Gehring, Niels H., Hofmann, Kay, Praefcke, Gerrit J. K., Dohmen, R. Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695498/
https://www.ncbi.nlm.nih.gov/pubmed/31417085
http://dx.doi.org/10.1038/s41467-019-11549-3

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